A young woman with cholestasis and ductopenia.

This patient was an 18-year-old woman with a history of psoriasis treated only with topical medication. No other conditions were recorded. She was the daughter of a patient who had undergone liver transplantation for liver cirrhosis secondary to chronic HCV infection and alcohol abuse. The patient presented with no symptoms but reported sporadic pain on her upper right quadrant of the abdomen. Inspection revealed no jaundice, weight loss, anorexia, asthenia, or pruritus. She usually smoked 4-5 cigarettes a day, drank no alcohol, and had no known allergies. She was referred to us after being diagnosed with hypertransaminasemia during routine family follow-up. Serum parameters included: GOT = 105 IU/L; GPT = 97 IU/L; AF = 355 IU/L; GGT = 344 IU/L.